Association of TP53 rs1042522 G > C, MDM2 rs2279744 T > G, and miR-34b/c rs4938723 T > C polymorphisms with aneuploidy pregnancy susceptibility

• Main Authors: Ying Chan (Author), Weiming Xu (Author), Yan Feng (Author), Yan Zhang (Author), Suyun Li (Author), Zibiao Geng (Author), Zhijiao Liu (Author), Qingfen Zhao (Author), Jinman Zhang (Author), Baosheng Zhu (Author)
• Format: Book
• Published: BMC, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Aneuploidy pregnancy is a severe major birth defect and causes about 50% spontaneous miscarriages with unknown etiology. To date, only a few epidemiological studies with small sample sizes have investigated the risk factors for aneuploidy pregnancy. TP53, MDM2, and miR-34b/c gene...