Identification of Anti-Persister Activity against Uropathogenic Escherichia coli from a Clinical Drug Library

• Main Authors: Hongxia Niu (Author), Peng Cui (Author), Wanliang Shi (Author), Shuo Zhang (Author), Jie Feng (Author), Yong Wang (Author), David Sullivan (Author), Wenhong Zhang (Author), Bingdong Zhu (Author), Ying Zhang (Author)
• Format: Book
• Published: MDPI AG, 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Uropathogenic E. coli is a major cause of urinary tract infections (UTIs), but current antibiotics do not always effectively clear the persistent infection. To identify drugs that eliminate uropathogenic E. coli persisters, we screened a clinical drug library consisting of 1524 compounds using high...