Reduction of pro-tumorigenic activity of human prostate cancer-associated fibroblasts using Dlk1 or SCUBE1

• मुख्य लेखकों: Brigid Orr (लेखक), O. Cathal Grace (लेखक), Pam Brown (लेखक), Antony C. P. Riddick (लेखक), Grant D. Stewart (लेखक), Omar E. Franco (लेखक), Simon W. Hayward (लेखक), Axel A. Thomson (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2013-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

SUMMARY Human prostatic cancer-associated fibroblasts (CAFs) can elicit malignant changes in initiated but non-tumorigenic human prostate epithelium, demonstrating that they possess pro-tumorigenic properties. We set out to reduce the pro-tumorigenic activity of patient CAFs using the Dlk1 and SCUBE...