Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer

• Main Authors: Ga Hee Kim (Author), Ji Eun Won (Author), Yeongseon Byeon (Author), Min Gi Kim (Author), Tae In Wi (Author), Jae Myeong Lee (Author), Yun-Yong Park (Author), Jeong-Won Lee (Author), Tae Heung Kang (Author), In Duk Jung (Author), Byung Cheol Shin (Author), Hyung Jun Ahn (Author), Young Joo Lee (Author), Anil K. Sood (Author), Hee Dong Han (Author), Yeong-Min Park (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Angiogenesis plays an essential role in the growth and metastasis of tumor cells, and the modulation of angiogenesis can be an effective approach for cancer therapy. We focused on silencing the angiogenic gene PLXDC1 as an important factor for anti-angiogenesis tumor therapy. Herein, we developed PL...