Glycine mitigates renal oxidative stress by suppressing Nox4 expression in rats with streptozotocin-induced diabetes

• Main Authors: Ziwei Wang (Author), Junqing Zhang (Author), Limei Wang (Author), Wei Li (Author), Lei Chen (Author), Jingjing Li (Author), Dan Zhao (Author), Hong Zhang (Author), Xiaohui Guo (Author)
• Format: Book
• Published: Elsevier, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glycine exerts renoprotective effects, but the mechanism remains unclear. Glycine is increasingly recognized as a factor that attenuates oxidative stress, a key mechanism underlying diabetic nephropathy. In this study, we investigated the effects of glycine on diabetic renal injury and oxidative str...