Phosphodiesterase 4 inhibitors and db-cAMP inhibit TNF-α release from human mononuclear cells. Effects of cAMP and cGMP-dependent protein kinase inhibitors

We investigated the effects of specific inhibitors of cAMP-dependent protein kinase (PKA) and cGMP-dependent protein kinase (PKG) on the inhibitory activity of phosphodiesterase (PDE) type 4 inhibitors and of the cell permeable analogue of cAMP, db-cAMP on LPS-induced TNF-α release from human mononu...

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Main Authors: A. Hichami (Author), E. Boichot (Author), N. Germain (Author), E. Berdyshev (Author), O. Coqueret (Author), V. Lagente (Author)
Formato: Livro
Publicado em: Hindawi Limited, 1996-01-01T00:00:00Z.
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