Involvement of organic cation transporter-3 and plasma membrane monoamine transporter in serotonin uptake in human brain vascular smooth muscle cells

• Main Authors: Rachel Wai-sum Li (Author), Cui eYang (Author), Yiu-Wa eKwan (Author), Shun-Wan eChan (Author), Simon Ming-Yuen Lee (Author), George Pak-Heng Leung (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The serotonin (5-HT) uptake system is supposed to play a crucial part in vascular functions by fine-tuning the local concentration of 5-HT in the vicinity of 5-HT2 receptors in vascular smooth muscle cells. In this study, the mechanism of 5-HT uptake in human brain vascular smooth muscle cells (HBVS...