Surface density of polyarginine influence the size, zeta potential, cellular uptake and tissue distribution of the nanostructured lipid carrier

• Main Authors: Mingshuang Sun (Author), Zhihong Zhu (Author), Huixin Wang (Author), Cuiyan Han (Author), Dandan Liu (Author), Lei Tian (Author), Xinggang Yang (Author), Weisan Pan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Poly-arginines are strong tools to elevate the cellular uptake of nanopreparations. To learn the influence of poly-arginine (RRRRRRRR, R8) density on a series of properties of nanostructured lipid carrier (NLC), we build six R8 modified NLCs with different R8 densities (nR-NLC, where n represents th...