Synthesis of Novel Conjugated Linoleic Acid (CLA)-Coated Superparamagnetic Iron Oxide Nanoparticles (SPIONs) for the Delivery of Paclitaxel with Enhanced In Vitro Anti-Proliferative Activity on A549 Lung Cancer Cells

• Autori principali: Lindokuhle M. Ngema (Autore), Samson A. Adeyemi (Autore), Thashree Marimuthu (Autore), Philemon Ubanako (Autore), Daniel Wamwangi (Autore), Yahya E. Choonara (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The application of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) as a nanomedicine for Non-Small Cell Lung Carcinoma (NSCLC) can provide effective delivery of anticancer drugs with minimal side-effects. SPIONs have the flexibility to be modified to achieve enhanced oading of hydrophobic antica...