EV-mediated promotion of myogenic differentiation is dependent on dose, collection medium, and isolation method

• Auteurs principaux: Britt Hanson (Auteur), Ioulia Vorobieva (Auteur), Wenyi Zheng (Auteur), Mariana Conceição (Auteur), Yulia Lomonosova (Auteur), Imre Mäger (Auteur), Pier Lorenzo Puri (Auteur), Samir El Andaloussi (Auteur), Matthew J.A. Wood (Auteur), Thomas C. Roberts (Auteur)
• Format: Livre
• Publié: Elsevier, 2023-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Extracellular vesicles (EVs) have been implicated in the regulation of myogenic differentiation. C2C12 murine myoblast differentiation was reduced following treatment with GW4869 or heparin (to inhibit exosome biogenesis and EV uptake, respectively). Conversely, treatment with C2C12 myotube-conditio...