Multilayered Polyurethane/Poly(vinyl alcohol) Nanofibrous Mats for Local Topotecan Delivery as a Potential Retinoblastoma Treatment

• Main Authors: Radka Hobzova (Author), Jakub Sirc (Author), Kusum Shrestha (Author), Barbora Mudrova (Author), Zuzana Bosakova (Author), Miroslav Slouf (Author), Marcela Munzarova (Author), Jan Hrabeta (Author), Tereza Feglarova (Author), Ana-Irina Cocarta (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Local chemotherapy using polymer drug delivery systems has the potential to treat some cancers, including intraocular retinoblastoma, which is difficult to treat with systemically delivered drugs. Well-designed carriers can provide the required drug concentration at the target site over a prolonged...