Effects of vancomycin‐induced gut microbiome alteration on the pharmacodynamics of metformin in healthy male subjects

• मुख्य लेखकों: Eunwoo Kim (लेखक), Andrew Hyoungjin Kim (लेखक), Yujin Lee (लेखक), Sang Chun Ji (लेखक), Joo‐Youn Cho (लेखक), Kyung‐Sang Yu (लेखक), Jae‐Yong Chung (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2021-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Metformin is a major treatment for type 2 diabetes. This study was conducted to investigate the impact of gut microbiome dysbiosis on the pharmacokinetics and antihyperglycemic effects of metformin. Healthy adult males aged 19-45 years with no defecation abnormalities were recruited for thi...