Analytic optimization of Plasmodium falciparum marker gene haplotype recovery from amplicon deep sequencing of complex mixtures.

• Main Authors: Zena Lapp (Author), Elizabeth Freedman (Author), Kathie Huang (Author), Christine F Markwalter (Author), Andrew A Obala (Author), Wendy Prudhomme-O'Meara (Author), Steve M Taylor (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Molecular epidemiologic studies of malaria parasites and other pathogens commonly employ amplicon deep sequencing (AmpSeq) of marker genes derived from dried blood spots (DBS) to answer public health questions related to topics such as transmission and drug resistance. As these methods are increasin...