TPGS-b-PBAE Copolymer-Based Polyplex Nanoparticles for Gene Delivery and Transfection In Vivo and In Vitro

• Autors principals: Jiahui Ding (Autor), Handan Zhang (Autor), Tianli Dai (Autor), Xueqin Gao (Autor), Zhongyuan Yin (Autor), Qiong Wang (Autor), Mengqi Long (Autor), Songwei Tan (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2024-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Poly (β-amino ester) (PBAE) is an exceptional non-viral vector that is widely used in gene delivery, owing to its exceptional biocompatibility, easy synthesis, and cost-effectiveness. However, it carries a high surface positive charge that may cause cytotoxicity. Therefore, hydrophilic d-α-tocophero...