Emulated Clinical Trials from Longitudinal Real-World Data Efficiently Identify Candidates for Neurological Disease Modification: Examples from Parkinson's Disease

• Main Authors: Daphna Laifenfeld (Author), Chen Yanover (Author), Michal Ozery-Flato (Author), Oded Shaham (Author), Michal Rosen-Zvi (Author), Nirit Lev (Author), Yaara Goldschmidt (Author), Iris Grossman (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Real-world healthcare data hold the potential to identify therapeutic solutions for progressive diseases by efficiently pinpointing safe and efficacious repurposing drug candidates. This approach circumvents key early clinical development challenges, particularly relevant for neurological diseases,...