Fabrication of Ion-Crosslinking Aminochitosan Nanoparticles for Encapsulation and Slow Release of Curcumin

• Main Authors: Xiaoxiao Sun (Author), Dongyan Yu (Author), Zhuoyang Ying (Author), Chuqiao Pan (Author), Nan Wang (Author), Fangfang Huang (Author), Junhong Ling (Author), Xiao-kun Ouyang (Author)
• Format: Book
• Published: MDPI AG, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Curcumin (Cur) has anticancer activities but has poor stability, which can be improved using carrier materials. In this study, chitosan was aminated to increase the number of amino groups on its surface, modified with folic acid (FA), and then made into nanoparticles by ionic crosslinking. Owing to...