Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies

Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies

Bisoprolol hemifumarate (BH) is an antihypertensive drug that is used as first-line treatment for chronic hypertension and angina pectoris. Our study was performed to enhance the transdermal delivery of BH, a hydrophilic drug active with high molecular weight, through differently prepared hydrogels....

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Main Authors: Mahmoud H. Teaima (Author), Mohamed Azmi Ahmed Mohamed (Author), Randa Tag Abd El Rehem (Author), Saadia A. Tayel (Author), Mohamed A. El-Nabarawi (Author), Shahinaze A. Fouad (Author)
Format: Book
Published: MDPI AG, 2021-05-01T00:00:00Z.
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