MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice: Parasitological and Cardiological Outcomes.

• Main Authors: Isabela Cunha Navarro (Author), Frederico Moraes Ferreira (Author), Helder I Nakaya (Author), Monique Andrade Baron (Author), Gláucia Vilar-Pereira (Author), Isabela Resende Pereira (Author), Ana Maria Gonçalves Silva (Author), Juliana Monte Real (Author), Thales De Brito (Author), Christophe Chevillard (Author), Joseli Lannes-Vieira (Author), Jorge Kalil (Author), Edecio Cunha-Neto (Author), Ludmila Rodrigues Pinto Ferreira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chagas disease is caused by the parasite Trypanosoma cruzi, and it begins with a short acute phase characterized by high parasitemia followed by a life-long chronic phase with scarce parasitism. Cardiac involvement is the most prominent manifestation, as 30% of infected subjects will develop abnorma...