Mechanisms of vascular damage by hemorrhagic snake venom metalloproteinases: tissue distribution and in situ hydrolysis.

• المؤلفون الرئيسيون: Cristiani Baldo (مؤلف), Colin Jamora (مؤلف), Norma Yamanouye (مؤلف), Telma M Zorn (مؤلف), Ana M Moura- (مؤلف)
• التنسيق: كتاب
• منشور في: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

BACKGROUND: Envenoming by viper snakes constitutes an important public health problem in Brazil and other developing countries. Local hemorrhage is an important symptom of these accidents and is correlated with the action of snake venom metalloproteinases (SVMPs). The degradation of vascular basemen...