Model-Based Analysis of In Vivo Release Data of Levonorgestrel Implants: Projecting Long-Term Systemic Exposure

• Main Authors: Soyoung Kim (Author), Brian Cicali (Author), Michelle Pressly (Author), Lais Da Silva (Author), Thomas Wendl (Author), Valvanera Vozmediano (Author), Stephan Schmidt (Author), Rodrigo Cristofoletti (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Levonorgestrel (LNG) is a progestin used in many contraceptive formulations, including subcutaneous implants. There is an unmet need for developing long-acting formulations for LNG. To develop long-acting formulations, release functions need to be investigated for LNG implant. Therefore, a release m...