Towards the Oral Treatment of Ileo-Colonic Inflammatory Bowel Disease with Infliximab Tablets: Development and Validation of the Production Process

• Hlavní autoři: Bahez Gareb (Autor), Silke Posthumus (Autor), Max Beugeling (Autor), Pauline Koopmans (Autor), Daan J. Touw (Autor), Gerard Dijkstra (Autor), Jos G.W. Kosterink (Autor), Henderik W. Frijlink (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2019-08-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Infliximab (IFX) is an intravenously administered monoclonal antibody antagonizing the effects of tumor necrosis factor-alpha (TNF) systemically and is efficacious in the treatment of inflammatory bowel disease (IBD). However, studies suggest that the anti-inflammatory effects result from local immu...