Adjuvant role of Ocimum sanctum hydroalcoholic extract with carbamazepine and phenytoin in experimental model of acute seizures

• Main Authors: Sudhir Chandra Sarangi (Author), Soumya Sucharita Pattnaik (Author), Dipesh Joshi (Author), P. Prarthana Chandra (Author), Thomas Kaleekal (Author)
• Format: Book
• Published: Elsevier, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: This study assessed adjuvant potential of Ocimum sanctum hydroalcoholic extract (OSHE) with antiepileptic drugs (AEDs) carbamazepine (CBZ) and phenytoin (PHT) in maximal electroshock seizure (MES) model in male Wistar rats. Material and Methods: Pharmacodynamic effect of OSHE (1000 mg/kg) w...