Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD

• Main Authors: Anna M.L. Coenen-Stass (Author), Helena Sork (Author), Sole Gatto (Author), Caroline Godfrey (Author), Amarjit Bhomra (Author), Kaarel Krjutškov (Author), Jonathan R. Hart (Author), Jakub O. Westholm (Author), Liz O'Donovan (Author), Andreas Roos (Author), Hanns Lochmüller (Author), Pier Lorenzo Puri (Author), Samir EL Andaloussi (Author), Matthew J.A. Wood (Author), Thomas C. Roberts (Author)
• Format: Bog
• Udgivet: Elsevier, 2018-12-01T00:00:00Z.
• Fag: article
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Extracellular small RNAs (sRNAs), including microRNAs (miRNAs), are promising biomarkers for diseases such as Duchenne muscular dystrophy (DMD), although their biological relevance is largely unknown. To investigate the relationship between intracellular and extracellular sRNA levels on a global sca...