PEG-Lipid-PLGA Hybrid Particles for Targeted Delivery of Anti-Inflammatory Drugs

• Main Authors: Jana Ismail (Author), Lea C. Klepsch (Author), Philipp Dahlke (Author), Ekaterina Tsarenko (Author), Antje Vollrath (Author), David Pretzel (Author), Paul M. Jordan (Author), Kourosh Rezaei (Author), Justyna A. Czaplewska (Author), Steffi Stumpf (Author), Baerbel Beringer-Siemers (Author), Ivo Nischang (Author), Stephanie Hoeppener (Author), Oliver Werz (Author), Ulrich S. Schubert (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hybrid nanoparticles (HNPs) were designed by combining a PLGA core with a lipid shell that incorporated PEG-Lipid conjugates with various functionalities (-RGD, -cRGD, -NH₂, and -COOH) to create targeted drug delivery systems. Loaded with a neutral lipid orange dye, the HNPs w...