Formulation and Evaluation of a Drug-in-Adhesive Patch for Transdermal Delivery of Colchicine

• Main Authors: Yaran Lei (Author), Guobao Yang (Author), Feng Du (Author), Jiahe Yi (Author), Liangzhu Quan (Author), Hanhan Liu (Author), Xun Zhou (Author), Wei Gong (Author), Jing Han (Author), Yuli Wang (Author), Chunsheng Gao (Author)
• Format: Bog
• Udgivet: MDPI AG, 2022-10-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Gout is one of the most prevalent rheumatic diseases, globally. Colchicine (COL) is the first-line drug used for the treatment of acute gout. However, the oral administration of COL is restricted, owing to serious adverse reactions. Therefore, this study aimed to develop a drug-in-adhesive (DIA) pat...