Novel NO-TZDs and trimethoxychalcone-based DHPMs: design, synthesis, and biological evaluation as potential VEGFR-2 inhibitors

Novel NO-TZDs and trimethoxychalcone-based DHPMs: design, synthesis, and biological evaluation as potential VEGFR-2 inhibitors

Novel series of nitric oxide-releasing thiazolidine-2,4-diones (NO-TZD-3a-d,5,6) and 3,4,5-trimethoxychalcone-based multifunctional 1,4-dihydropyrimidines (CDHPM-10a-g) have been designed and synthesised as potent broad-spectrum anticancer agents with potential VEGFR-2 inhibition. The designed analo...

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Main Authors: Mater H. Mahnashi (Author), Mohammed Nahari (Author), Hassan Almasoudi (Author), Abdulaziz Alhasaniah (Author), Sara Elgazwi (Author), Mahrous A. Abou-Salim (Author)
Format: Book
Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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