SLC7A11 as a Gateway of Metabolic Perturbation and Ferroptosis Vulnerability in Cancer
SLC7A11 is a cell transmembrane protein composing the light chain of system xc<sup>−</sup>, transporting extracellular cystine into cells for cysteine production and GSH biosynthesis. SLC7A11 is a critical gateway for redox homeostasis by maintaining the cellular levels of GSH that count...
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MDPI AG,
2022-12-01T00:00:00Z.
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