Curcumin attenuates renal interstitial fibrosis of obstructive nephropathy by suppressing epithelial-mesenchymal transition through inhibition of the TLR4/NF-кB and PI3K/AKT signalling pathways

Context Renal interstitial fibrosis (RIF) is characterized by the accumulation of inflammatory cytokines and epithelial-mesenchymal transition (EMT). Curcumin exerts antifibrogenic, anti-inflammatory and antiproliferative effects. Objective To explore the mechanisms underlying the effects of curcumi...

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Main Authors: Zhaohui Wang (Author), Zhi Chen (Author), Bingsheng Li (Author), Bo Zhang (Author), Yongchao Du (Author), Yuhang Liu (Author), Yao He (Author), Xiang Chen (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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