Development of naringenin-O-alkylamine derivatives as multifunctional agents for the treatment of Alzheimer's disease

• Main Authors: Jing Yang (Author), Yi Zhou (Author), Yujuan Ban (Author), Jing Mi (Author), Ying He (Author), Xinjuan Li (Author), Zhengwei Liu (Author), Keren Wang (Author), Gaofeng Zhu (Author), Wenmin Liu (Author), Zhenghuai Tan (Author), Zhipei Sang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study, a series of naringenin-O-alkylamine derivatives were designed and obtained by introducing an alkylamine fragment into the naringenin skeleton. The in vitro biological activity results revealed that compounds 5f and 7k showed good antioxidant activity with ORAC values of 2.3eq and 1.2e...