Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches
The papain-like protease (PLpro) is vital for the replication of coronaviruses (CoVs), as well as for escaping innate-immune responses of the host. Hence, it has emerged as an attractive antiviral drug-target. In this study, computational approaches were employed, mainly the structure-based virtual...
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Elsevier,
2020-12-01T00:00:00Z.
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