Jakinibs of All Trades: Inhibiting Cytokine Signaling in Immune-Mediated Pathologies

• मुख्य लेखकों: Madison Alexander (लेखक), Yiming Luo (लेखक), Giorgio Raimondi (लेखक), John J. O'Shea (लेखक), Massimo Gadina (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Over the last 25 years, inhibition of Janus kinases (JAKs) has been pursued as a modality for treating various immune and inflammatory disorders. While the clinical development of JAK inhibitors (jakinibs) began with the investigation of their use in allogeneic transplantation, their widest successf...