Phenotypic miRNA Screen Identifies miR-26b to Promote the Growth and Survival of Endothelial Cells

• Main Authors: Andrea Martello (Author), David Mellis (Author), Marco Meloni (Author), Alison Howarth (Author), Daniel Ebner (Author), Andrea Caporali (Author), Ayman Al Haj Zen (Author)
• Format: Book
• Published: Elsevier, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endothelial cell (EC) proliferation is a crucial event in physiological and pathological angiogenesis. MicroRNAs (miRNAs) have emerged as important modulators of the angiogenic switch. Here we conducted high-content screening of a human miRNA mimic library to identify novel regulators of EC growth s...