Metabolomics integrated with network pharmacology of blood-entry constituents reveals the bioactive component of Xuefu Zhuyu decoction and its angiogenic effects in treating traumatic brain injury

• Egile Nagusiak: Teng Li (Egilea), Lianglin Zhang (Egilea), Menghan Cheng (Egilea), En Hu (Egilea), Qiuju Yan (Egilea), Yao Wu (Egilea), Weikang Luo (Egilea), Hong Su (Egilea), Zhe Yu (Egilea), Xin Guo (Egilea), Quan Chen (Egilea), Fei Zheng (Egilea), Haigang Li (Egilea), Wei Zhang (Egilea), Tao Tang (Egilea), Jiekun Luo (Egilea), Yang Wang (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2024-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Xuefu Zhuyu decoction (XFZYD) has been extensively utilized to treat traumatic brain injury (TBI). However, the bioactive compounds and the underlying mechanisms have not yet been elucidated. Objectives This study aimed to investigate the bioactive constituents of XFYZD that are...