Force-induced Caspase-1-dependent pyroptosis regulates orthodontic tooth movement

• Main Authors: Liyuan Chen (Author), Huajie Yu (Author), Zixin Li (Author), Yu Wang (Author), Shanshan Jin (Author), Min Yu (Author), Lisha Zhu (Author), Chengye Ding (Author), Xiaolan Wu (Author), Tianhao Wu (Author), Chunlei Xun (Author), Yanheng Zhou (Author), Danqing He (Author), Yan Liu (Author)
• Format: Book
• Published: Nature Publishing Group, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Pyroptosis, an inflammatory caspase-dependent programmed cell death, plays a vital role in maintaining tissue homeostasis and activating inflammatory responses. Orthodontic tooth movement (OTM) is an aseptic force-induced inflammatory bone remodeling process mediated by the activation of pe...