Inhibition of Tityus serrulatus venom hyaluronidase affects venom biodistribution.

• Main Authors: Bárbara Bruna Ribeiro de Oliveira-Mendes (Author), Sued Eustáquio Mendes Miranda (Author), Douglas Ferreira Sales-Medina (Author), Bárbara de Freitas Magalhães (Author), Yan Kalapothakis (Author), Renan Pedra de Souza (Author), Valbert Nascimento Cardoso (Author), André Luís Branco de Barros (Author), Clara Guerra-Duarte (Author), Evanguedes Kalapothakis (Author), Carolina Campolina Rebello Horta (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>The hyaluronidase enzyme is generally known as a spreading factor in animal venoms. Although its activity has been demonstrated in several organisms, a deeper knowledge about hyaluronidase and the venom spreading process from the bite/sting site until its elimination f...