Neuroprotective and Angiogenesis Effects of Levetiracetam Following Ischemic Stroke in Rats

• Main Authors: Xiang Yao (Author), Wenping Yang (Author), Zhendong Ren (Author), Haoran Zhang (Author), Dafa Shi (Author), Yanfei Li (Author), Ziyang Yu (Author), Qiu Guo (Author), Guangwei Yang (Author), Yingjiang Gu (Author), Hairong Zhao (Author), Ke Ren (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The present study explored whether levetiracetam (LEV) could protect against experimental brain ischemia and enhance angiogenesis in rats, and investigated the potential mechanisms in vivo and in vitro.Methods: The middle cerebral artery was occluded for 60 min to induce middle cerebral a...