Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages

Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages

Varenicline is a widely used and effective drug for smoking cessation. We have previously reported experimental evidence suggesting that varenicline increases the risk of cardiovascular events. Varenicline progresses atherosclerotic plaque formation in apolipoprotein E knockout (ApoE KO) mice. This...

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Main Authors: Mitsuhisa Koga (Author), Yuki Kanaoka (Author), Koshun Inada (Author), Sai Omine (Author), Yasufumi Kataoka (Author), Atsushi Yamauchi (Author)
Format: Book
Published: Elsevier, 2020-06-01T00:00:00Z.
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