Inhalationally Administered Semifluorinated Alkanes (SFAs) as Drug Carriers in an Experimental Model of Acute Respiratory Distress Syndrome

• Main Authors: Matthias Otto (Author), Jörg Krebs (Author), Peter Welker (Author), René Holm (Author), Manfred Thiel (Author), Luciano Gattinoni (Author), Michael Quintel (Author), Charalambos Tsagogiorgas (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aerosol therapy in patients suffering from acute respiratory distress syndrome (ARDS) has so far failed in improving patients' outcomes. This might be because dependent lung areas cannot be reached by conventional aerosols. Due to their physicochemical properties, semifluorinated alkanes (SFAs)...