NF1+/ex42del miniswine model the cellular disruptions and behavioral presentations of NF1‐associated cognitive and motor impairment

• Main Authors: Vicki J. Swier (Author), Katherine A. White (Author), Pedro L. Negrão de Assis (Author), Tyler B. Johnson (Author), Hannah G. Leppert (Author), Mitchell J. Rechtzigel (Author), David K. Meyerholz (Author), Rebecca D. Dodd (Author), Dawn E. Quelle (Author), Rajesh Khanna (Author), Christopher S. Rogers (Author), Jill M. Weimer (Author)
• Format: Book
• Published: Wiley, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Cognitive or motor impairment is common among individuals with neurofibromatosis type 1 (NF1), an autosomal dominant tumor‐predisposition disorder. As many as 70% of children with NF1 report difficulties with spatial/working memory, attention, executive function, and fine motor movements. I...