Role of Rac1 in augmented endothelin-1-induced bronchial contraction in airway hyperresponsive mice

• Main Authors: Yuki Kai (Author), Risako Kon (Author), Nobutomo Ikarashi (Author), Yoshihiko Chiba (Author), Junzo Kamei (Author), Hiroyasu Sakai (Author)
• Format: Book
• Published: Elsevier, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It has recently been exhibited that Rac1 expression is increased in the bronchial tissue of a murine model with repeated antigen-challenged airway hyperresponsiveness (AHR). In the present study, the role of Rac1 in endothelin-1 (ET-1)-induced bronchial contraction and myosin light chain (MLC) phosp...