An mRNA vaccine elicits STING-dependent antitumor immune responses

• मुख्य लेखकों: Zhe Chen (लेखक), Chaoyang Meng (लेखक), Junhua Mai (लेखक), Yongbin Liu (लेखक), Hangwen Li (लेखक), Haifa Shen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Lipid-formulated RNA vaccines have been widely used for disease prevention and treatment, yet their mechanism of action and individual components contributing to such actions remain to be delineated. Here, we show that a therapeutic cancer vaccine composed of a protamine/mRNA core and a lipid shell...