Blocking the Trigger: Inhibition of the Initiation of Bacterial Chromosome Replication as an Antimicrobial Strategy

All bacterial cells must duplicate their genomes prior to dividing into two identical daughter cells. Chromosome replication is triggered when a nucleoprotein complex, termed the orisome, assembles, unwinds the duplex DNA, and recruits the proteins required to establish new replication forks. Obviou...

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Bibliographic Details
Main Authors: Julia E. Grimwade (Author), Alan C. Leonard (Author)
Format: Book
Published: MDPI AG, 2019-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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