The Protective Effect of Alpha-Mangostin against Cisplatin-Induced Cell Death in LLC-PK1 Cells is Associated to Mitochondrial Function Preservation

• Главные авторы: Laura María Reyes-Fermín (Автор), Sabino Hazael Avila-Rojas (Автор), Omar Emiliano Aparicio-Trejo (Автор), Edilia Tapia (Автор), Isabel Rivero (Автор), José Pedraza-Chaverri (Автор)
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• Опубликовано: MDPI AG, 2019-05-01T00:00:00Z.
• Предметы: article
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Cis-dichlorodiammineplatinum II (CDDP) is a chemotherapeutic agent that induces nephrotoxicity by different mechanisms, including oxidative stress, mitochondrial dysfunction, autophagy, and endoplasmic reticulum stress. This study aimed to evaluate if the protective effects of the antioxidant alpha-...