Supplemental thiamine for the treatment of acute heart failure syndrome: a randomized controlled trial

• Main Authors: Howard A. Smithline (Author), Michael Donnino (Author), Fidela S. J. Blank (Author), Richard Barus (Author), Ryan A. Coute (Author), Alexander B. Knee (Author), Paul Visintainer (Author)
• Format: Book
• Published: BMC, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The purpose of this pilot study was to determine if a definitive clinical trial of thiamine supplementation was warranted in patients with acute heart failure. We hypothesized that thiamine, when added to standard of care, would improve dyspnea (primary outcome) in hospitalized p...