Effect of taxifolin on methotrexate-induced oxidative and inflammatory oral mucositis in rats: biochemical and histopathological evaluation

• Main Authors: Zeynep BAYRAMOGLU (Author), Behzad MOKHTARE (Author), Ali Sefa MENDIL (Author), Taha Abdulkadir COBAN (Author), Renad MAMMADOV (Author), Seval BULUT (Author), Zeynep SULEYMAN (Author), Halis SULEYMAN (Author)
• Format: Book
• Published: University of São Paulo, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The role of oxidative stress, as well as inflammation in the pathogenesis of methotrexate (MTX)-induced oral mucositis, is a known fact. The anti-inflammatory, antitumor, antimicrobial, and antioxidant properties of taxifolin-the effect we tested against MTX-induced oral mucosal damage-are...