Physiological relevance of protein-glycosylation to pathogenesis of diabetes

• 主要な著者: Kazuaki Ohtsubo (著者), Naoyuki Taniguchi (著者)
• フォーマット: 図書
• 出版事項: Japanese Society of Physical Fitness and Sports Medicine, 2014-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Pancreatic β cells express glucose transporter-2 (GLUT2) on the cell surface as a glucose sensor molecule for appropriate insulin secretion. Disappearance of GLUT2 from the β cell surface is one of the early markers of the onset of type 2 diabetes, though the molecular mechanism has not been well un...