Mechanism of Hydrophobic Bile Acid-Induced Hepatocyte Injury and Drug Discovery
Cholestatic liver disease is caused by the obstruction of bile synthesis, transport, and excretion in or outside the liver by a variety of reasons. Long-term persistent cholestasis in the liver can trigger inflammation, necrosis, or apoptosis of hepatocytes. Bile acid nuclear receptors have received...
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2020-07-01T00:00:00Z.
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