TGFβ level in healthy and children with Marfan syndrome-effective reduction under sartan therapy

• मुख्य लेखकों: Veronika C. Stark (लेखक), Jakob Olfe (लेखक), Daniel Diaz-Gil (लेखक), Yskert von Kodolitsch (लेखक), Rainer Kozlik-Feldmann (लेखक), Johannes Reincke (लेखक), Maria Stark (लेखक), Peter Wiegand (लेखक), Tanja Zeller (लेखक), Thomas S. Mir (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

IntroductionTransforming growth factor β (TGFβ) metabolism plays an important role in the pathogenesis of Marfan syndrome (MFS). Accordingly, drug therapy uses TGFβ receptor blockade to slow down the cardiovascular manifestations, above all aortic root dilatation. Angiotensin II type 1 receptor bloc...