Calcium Dobesilate Reverses Cognitive Deficits and Anxiety-Like Behaviors in the D-Galactose-Induced Aging Mouse Model through Modulation of Oxidative Stress

• Main Authors: Elham Hakimizadeh (Author), Mohammad Zamanian (Author), Lydia Giménez-Llort (Author), Clara Sciorati (Author), Marjan Nikbakhtzadeh (Author), Małgorzata Kujawska (Author), Ayat Kaeidi (Author), Jalal Hassanshahi (Author), Iman Fatemi (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The long-term treatment of mice with D-galactose (D-gal) induces the overproduction of reactive oxygen species (ROS) and is a well-accepted experimental model of oxidative stress-linked cognitive disorders in physiological aging. Calcium dobesilate (CaD, Doxium^®) is an establi...