Calcium Dobesilate Reverses Cognitive Deficits and Anxiety-Like Behaviors in the D-Galactose-Induced Aging Mouse Model through Modulation of Oxidative Stress

• Auteurs principaux: Elham Hakimizadeh (Auteur), Mohammad Zamanian (Auteur), Lydia Giménez-Llort (Auteur), Clara Sciorati (Auteur), Marjan Nikbakhtzadeh (Auteur), Małgorzata Kujawska (Auteur), Ayat Kaeidi (Auteur), Jalal Hassanshahi (Auteur), Iman Fatemi (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The long-term treatment of mice with D-galactose (D-gal) induces the overproduction of reactive oxygen species (ROS) and is a well-accepted experimental model of oxidative stress-linked cognitive disorders in physiological aging. Calcium dobesilate (CaD, Doxium^®) is an establi...