The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data platform.

• Main Authors: Brittany J Maguire (Author), Prabin Dahal (Author), Sumayyah Rashan (Author), Roland Ngu (Author), Anca Boon (Author), Colin Forsyth (Author), Nathalie Strub-Wourgaft (Author), Eric Chatelain (Author), Fabiana Barreira (Author), Sergio Sosa-Estani (Author), Philippe J Guérin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6-7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses to addre...